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Patient Guide

Underactive Thyroid

Hypothyroidism — the signs, the tests, and how it's treated

Butterflygland in your neck that sets your body's pace
TSHthe main blood test — it rises when the thyroid is slow
Very treatablea simple daily tablet usually restores your levels
When your thyroid runs slow. Your thyroid is a small, butterfly-shaped gland in your neck that sets your body's pace. When it's underactive everything slows down — and the good news is it's common and very treatable.

Signs of an underactive thyroid

Tired & sluggish

Low energy and slowed down — sleeping more but still feeling tired.

Weight gain

Putting on weight or struggling to lose it, as your metabolism slows.

Feeling the cold

Feeling cold when others are comfortable, with cool hands and feet.

Dry skin & hair

Dry or rough skin, and dry, thinning hair or brittle nails.

Low mood & brain fog

Feeling flat or down, with slower thinking, memory or concentration.

Constipation & cramps

A sluggish gut, muscle aches or cramps, and sometimes heavier periods.

Borderline result? ("subclinical") Sometimes the TSH is only mildly up while your thyroid hormone (T4) is still normal. This often causes few or no symptoms and can settle on its own, so we may simply recheck in a few months. We're quicker to treat if the TSH is high, you have symptoms or thyroid antibodies, or you're pregnant or planning to be.

The treatment: thyroxine

Replaces the hormone

Levothyroxine (thyroxine) is the same hormone your thyroid makes — it simply tops it back up.

Taken as one tablet daily

Usually long-term

Often lifelong, especially with Hashimoto's — though some mild or temporary cases don't need it forever.

Some cases are only short-term

Fine-tuned by tests

We adjust the dose using your TSH blood test; it takes about 6 weeks to settle after a change.

Aiming to ease your symptoms

Getting the most from your tablet

Take it well

  • Same time each day on an empty stomach — either morning (30–60 min before food or coffee) or bedtime, 3+ hours after eating
  • Swallow with water; coffee, milk and food lower how much you absorb
  • Keep iron, calcium, antacids and multivitamins about 4 hours apart from it
  • Don't stop suddenly; if you miss a dose, take it when you remember

Good to know

  • Tell us if you're pregnant or planning to be — you'll need more, and prompt testing
  • Once you're stable, occasional blood tests keep the dose right
  • Too much can cause over-active symptoms — palpitations, feeling wired, weight loss
  • If you still feel off once your TSH is normal, let's look for other causes too

Will I feel better?

Most people feel back to themselves once the dose is right, though it can take a few weeks. Tiredness and weight aren't always only the thyroid — so we treat you and your symptoms, not just the number.

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